In addition to the previous service mentioned to Ashland, Paintsville and Hazard from Lexington. Greyhound lines operated from Ashland to Pikeville via US 23 buses originated at Columbus Ohio stops in Kentucky included Cattletsburg, Louisa , Paintsville, Prestonsbrg, Allen and Pikeville.

In addition to Greyhound Pikeville was served  by Trailways with routes to Jenkins Kentucky and beyond with stops in Shelby, Indian Creek, Virgie, and Dorton, in Kentucky the route also went north to Williamson WV and Huntington and a another route operated to Millard Belcher and Mouth Card en route to Grundy , VA

In Ashland Trailways operated a route to Cincinnati which served Vanceburg, Maysville, Augusta and Covington

And Bristol - Jenkins Bus Lines offered service to Appalachian Virginia from  Harlan , Middlesboro and Jenkins and operated to Pineville from Harlan serving Blackmont and Wallins in Kentucky

Other services were operated from Albany , KY to Chattanooga by CC Bus Lines Inc.